BDBM50263946 6-(1H-imidazol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)butyl)pyridazin-3(2H)-one::CHEMBL523774

SMILES: CC(C)Oc1ccccc1N1CCN(CCCCn2nc(ccc2=O)-n2ccnc2)CC1

InChI Key: InChIKey=ILMAXPRFLXLJED-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50263946 (6-(1H-imidazol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)p...) Show SMILES CC(C)Oc1ccccc1N1CCN(CCCCn2nc(ccc2=O)-n2ccnc2)CC1 Show InChI InChI=1S/C24H32N6O2/c1-20(2)32-22-8-4-3-7-21(22)28-17-15-27(16-18-28)12-5-6-13-30-24(31)10-9-23(26-30)29-14-11-25-19-29/h3-4,7-11,14,19-20H,5-6,12-13,15-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 5140-5 (2008) Article DOI: 10.1016/j.bmcl.2008.07.084 BindingDB Entry DOI: 10.7270/Q2WS8V4S
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50263946 (6-(1H-imidazol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)p...) Show SMILES CC(C)Oc1ccccc1N1CCN(CCCCn2nc(ccc2=O)-n2ccnc2)CC1 Show InChI InChI=1S/C24H32N6O2/c1-20(2)32-22-8-4-3-7-21(22)28-17-15-27(16-18-28)12-5-6-13-30-24(31)10-9-23(26-30)29-14-11-25-19-29/h3-4,7-11,14,19-20H,5-6,12-13,15-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from SERT in human platelet membrane				Bioorg Med Chem Lett 18: 5140-5 (2008) Article DOI: 10.1016/j.bmcl.2008.07.084 BindingDB Entry DOI: 10.7270/Q2WS8V4S
					More data for this Ligand-Target Pair