BDBM50263951 4-(2-chlorophenyl)-N-methyl-N-(2-(piperidin-1-yl)ethyl)piperazine-1-carboxamide::CHEMBL489589

SMILES: CN(CCN1CCCCC1)C(=O)N1CCN(CC1)c1ccccc1Cl

InChI Key: InChIKey=RIIUHTQGDQYAKS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50263951 (4-(2-chlorophenyl)-N-methyl-N-(2-(piperidin-1-yl)e...) Show SMILES CN(CCN1CCCCC1)C(=O)N1CCN(CC1)c1ccccc1Cl Show InChI InChI=1S/C19H29ClN4O/c1-21(11-12-22-9-5-2-6-10-22)19(25)24-15-13-23(14-16-24)18-8-4-3-7-17(18)20/h3-4,7-8H,2,5-6,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of (R)-alpha-methylhistamine-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 18: 5101-6 (2008) Article DOI: 10.1016/j.bmcl.2008.07.125 BindingDB Entry DOI: 10.7270/Q2PC3268
					More data for this Ligand-Target Pair