null
SMILES: COc1cc2CCN(CCc3ccc(NC(=O)c4cccnc4NCc4ccncc4)cc3)Cc2cc1OC
InChI Key: InChIKey=IIXHUWSCQWCPGQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50265388 (CHEMBL4097071) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring compound concentration required ... | J Med Chem 60: 2930-2943 (2017) Article DOI: 10.1021/acs.jmedchem.6b01879 BindingDB Entry DOI: 10.7270/Q2CR5WT1 | |||||||||||
More data for this Ligand-Target Pair |