BDBM50265618 CHEMBL495533::N'-[(3Z)-1-Butyl-6-methoxy-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide

SMILES: CCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12

InChI Key: InChIKey=WADRTXVLNHGPCZ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50265618 (CHEMBL495533 | N'-[(3Z)-1-Butyl-6-methoxy-2-oxo-1,...) Show SMILES CCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12 |w:8.8| Show InChI InChI=1S/C20H21N3O3/c1-3-4-12-23-17-13-15(26-2)10-11-16(17)18(20(23)25)21-22-19(24)14-8-6-5-7-9-14/h5-11,13H,3-4,12H2,1-2H3,(H,22,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay				J Med Chem 52: 433-44 (2009) Article DOI: 10.1021/jm801353p BindingDB Entry DOI: 10.7270/Q20G3M2X
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50265618 (CHEMBL495533 | N'-[(3Z)-1-Butyl-6-methoxy-2-oxo-1,...) Show SMILES CCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12 |w:8.8| Show InChI InChI=1S/C20H21N3O3/c1-3-4-12-23-17-13-15(26-2)10-11-16(17)18(20(23)25)21-22-19(24)14-8-6-5-7-9-14/h5-11,13H,3-4,12H2,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay				J Med Chem 52: 433-44 (2009) Article DOI: 10.1021/jm801353p BindingDB Entry DOI: 10.7270/Q20G3M2X
					More data for this Ligand-Target Pair