null

SMILES: OC(=O)C1=Cc2cc(ccc2O[C@@H]1C(F)(F)F)S(F)(F)(F)(F)F

InChI Key: InChIKey=QVPDRFYJQHCIEB-VIFPVBQESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50266855 (CHEMBL4074716) Show SMILES OC(=O)C1=Cc2cc(ccc2O[C@@H]1C(F)(F)F)S(F)(F)(F)(F)F |r,t:3| Show InChI InChI=1S/C11H6F8O3S/c12-11(13,14)9-7(10(20)21)4-5-3-6(1-2-8(5)22-9)23(15,16,17,18)19/h1-4,9H,(H,20,21)/t9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human COX-1 preincubated for 15 mins followed by fluorometric substrate/heme addition for 15 mins subsequently incubated with arachidon...				J Med Chem 60: 4135-4146 (2017) Article DOI: 10.1021/acs.jmedchem.6b01484 BindingDB Entry DOI: 10.7270/Q2M32Z7Q
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50266855 (CHEMBL4074716) Show SMILES OC(=O)C1=Cc2cc(ccc2O[C@@H]1C(F)(F)F)S(F)(F)(F)(F)F |r,t:3| Show InChI InChI=1S/C11H6F8O3S/c12-11(13,14)9-7(10(20)21)4-5-3-6(1-2-8(5)22-9)23(15,16,17,18)19/h1-4,9H,(H,20,21)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of recombinant human COX-2 preincubated for 15 mins followed by fluorometric substrate/heme addition for 15 mins subsequently incubated wi...				J Med Chem 60: 4135-4146 (2017) Article DOI: 10.1021/acs.jmedchem.6b01484 BindingDB Entry DOI: 10.7270/Q2M32Z7Q
					More data for this Ligand-Target Pair