BDBM50267299 CHEMBL4092788

SMILES: COc1cc(N(C)CC(=O)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn2CCCc3cccc1c23

InChI Key: InChIKey=XXQBTAPKFINNKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50267299 (CHEMBL4092788) Show SMILES COc1cc(N(C)CC(=O)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn2CCCc3cccc1c23 Show InChI InChI=1S/C30H33N7O3/c1-6-27(38)32-23-15-24(26(40-5)16-25(23)36(4)18-28(39)35(2)3)34-30-31-13-12-22(33-30)21-17-37-14-8-10-19-9-7-11-20(21)29(19)37/h6-7,9,11-13,15-17H,1,8,10,14,18H2,2-5H3,(H,32,38)(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant cytoplasmic GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubated fo...				Eur J Med Chem 135: 12-23 (2017) Article DOI: 10.1016/j.ejmech.2017.04.036 BindingDB Entry DOI: 10.7270/Q28P630H
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