BDBM50267446 Ac-pTyr-Leu-Indoline-2-carboxylate-Gln-Thr-NH2::CHEMBL504633

SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1[C@@H](Cc2ccccc12)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

InChI Key: InChIKey=ZKTXWHQCBUBYPW-USPVEINMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50267446 (Ac-pTyr-Leu-Indoline-2-carboxylate-Gln-Thr-NH2 | C...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1[C@@H](Cc2ccccc12)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r| Show InChI InChI=1S/C35H48N7O12P/c1-18(2)15-26(40-33(48)25(38-20(4)44)16-21-9-11-23(12-10-21)54-55(51,52)53)35(50)42-27-8-6-5-7-22(27)17-28(42)34(49)39-24(13-14-29(36)45)32(47)41-30(19(3)43)31(37)46/h5-12,18-19,24-26,28,30,43H,13-17H2,1-4H3,(H2,36,45)(H2,37,46)(H,38,44)(H,39,49)(H,40,48)(H,41,47)(H2,51,52,53)/t19-,24+,25+,26+,28+,30+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Inhibition of Stat3 (unknown origin) by fluorescence polarization assay				J Med Chem 52: 2429-42 (2009) Article DOI: 10.1021/jm801491w BindingDB Entry DOI: 10.7270/Q28C9W4V
					More data for this Ligand-Target Pair