BDBM50267905 CHEMBL523603::cyclohexyl(4-(naphthalen-1-ylsulfonyl)-2-phenylpiperazin-1-yl)methanone

SMILES: O=C(C1CCCCC1)N1CCN(CC1c1ccccc1)S(=O)(=O)c1cccc2ccccc12

InChI Key: InChIKey=KWSTWVVXSGUPPV-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50267905 (CHEMBL523603 | cyclohexyl(4-(naphthalen-1-ylsulfon...) Show SMILES O=C(C1CCCCC1)N1CCN(CC1c1ccccc1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H30N2O3S/c30-27(23-13-5-2-6-14-23)29-19-18-28(20-25(29)22-11-3-1-4-12-22)33(31,32)26-17-9-15-21-10-7-8-16-24(21)26/h1,3-4,7-12,15-17,23,25H,2,5-6,13-14,18-20H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP level				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50267905 (CHEMBL523603 | cyclohexyl(4-(naphthalen-1-ylsulfon...) Show SMILES O=C(C1CCCCC1)N1CCN(CC1c1ccccc1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H30N2O3S/c30-27(23-13-5-2-6-14-23)29-19-18-28(20-25(29)22-11-3-1-4-12-22)33(31,32)26-17-9-15-21-10-7-8-16-24(21)26/h1,3-4,7-12,15-17,23,25H,2,5-6,13-14,18-20H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cells				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair