BDBM50268786 (R/S)-N-(5-fluoro-2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-indol-3-yl)-2-oxoacetamide::CHEMBL495615

SMILES: [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NC3CCc4cc(F)ccc34)c2c1

InChI Key: InChIKey=KCTWTQNQVBDHCG-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50268786 ((R/S)-N-(5-fluoro-2,3-dihydro-1H-inden-1-yl)-2-(5-...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NC3CCc4cc(F)ccc34)c2c1 Show InChI InChI=1S/C19H14FN3O4/c20-11-2-4-13-10(7-11)1-5-17(13)22-19(25)18(24)15-9-21-16-6-3-12(23(26)27)8-14(15)16/h2-4,6-9,17,21H,1,5H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha1beta2gamma2 receptor expressed in HEK293 cells				J Med Chem 52: 3723-34 (2009) Article DOI: 10.1021/jm9001154 BindingDB Entry DOI: 10.7270/Q2N58M89
					More data for this Ligand-Target Pair
GABA(A) receptor subunit alpha-2 (Rattus norvegicus (Rat))	BDBM50268786 ((R/S)-N-(5-fluoro-2,3-dihydro-1H-inden-1-yl)-2-(5-...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NC3CCc4cc(F)ccc34)c2c1 Show InChI InChI=1S/C19H14FN3O4/c20-11-2-4-13-10(7-11)1-5-17(13)22-19(25)18(24)15-9-21-16-6-3-12(23(26)27)8-14(15)16/h2-4,6-9,17,21H,1,5H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha2beta2gamma2 receptor expressed in HEK293 cells				J Med Chem 52: 3723-34 (2009) Article DOI: 10.1021/jm9001154 BindingDB Entry DOI: 10.7270/Q2N58M89
					More data for this Ligand-Target Pair
GABA A receptor alpha-5/beta-3/gamma-2 (RAT)	BDBM50268786 ((R/S)-N-(5-fluoro-2,3-dihydro-1H-inden-1-yl)-2-(5-...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NC3CCc4cc(F)ccc34)c2c1 Show InChI InChI=1S/C19H14FN3O4/c20-11-2-4-13-10(7-11)1-5-17(13)22-19(25)18(24)15-9-21-16-6-3-12(23(26)27)8-14(15)16/h2-4,6-9,17,21H,1,5H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha5beta3gamma2 receptor expressed in HEK293 cells				J Med Chem 52: 3723-34 (2009) Article DOI: 10.1021/jm9001154 BindingDB Entry DOI: 10.7270/Q2N58M89
					More data for this Ligand-Target Pair