BDBM50268787 (R/S)-2-(5-nitro-1H-indol-3-yl)-N-(5-nitro-2,3-dihydro-1H-inden-1-yl)-2-oxoacetamide::CHEMBL495616
SMILES: [O-][N+](=O)c1ccc2C(CCc2c1)NC(=O)C(=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O
InChI Key: InChIKey=YPSCSODEMUDTBM-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat)) | BDBM50268787 ((R/S)-2-(5-nitro-1H-indol-3-yl)-N-(5-nitro-2,3-dih...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Pisa Curated by ChEMBL | Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha1beta2gamma2 receptor expressed in HEK293 cells | J Med Chem 52: 3723-34 (2009) Article DOI: 10.1021/jm9001154 BindingDB Entry DOI: 10.7270/Q2N58M89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA(A) receptor subunit alpha-2 (Rattus norvegicus (Rat)) | BDBM50268787 ((R/S)-2-(5-nitro-1H-indol-3-yl)-N-(5-nitro-2,3-dih...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 513 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Pisa Curated by ChEMBL | Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha2beta2gamma2 receptor expressed in HEK293 cells | J Med Chem 52: 3723-34 (2009) Article DOI: 10.1021/jm9001154 BindingDB Entry DOI: 10.7270/Q2N58M89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA A receptor alpha-5/beta-3/gamma-2 (RAT) | BDBM50268787 ((R/S)-2-(5-nitro-1H-indol-3-yl)-N-(5-nitro-2,3-dih...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 749 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Pisa Curated by ChEMBL | Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha5beta3gamma2 receptor expressed in HEK293 cells | J Med Chem 52: 3723-34 (2009) Article DOI: 10.1021/jm9001154 BindingDB Entry DOI: 10.7270/Q2N58M89 | |||||||||||
More data for this Ligand-Target Pair |