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BDBM50269681 CHEMBL4077565

SMILES: CCCCCCCCCCOC(C(C)Oc1c(OC)cc(CC=C)cc1OC)c1ccc(O)c(OC)c1

InChI Key: InChIKey=HWNPJGWMFAHTOD-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269681   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8 (TRPM8)


(Homo sapiens (Human))		BDBM50269681
PNG
(CHEMBL4077565)
Show SMILES CCCCCCCCCCOC(C(C)Oc1c(OC)cc(CC=C)cc1OC)c1ccc(O)c(OC)c1
Show InChI InChI=1S/C31H46O6/c1-7-9-10-11-12-13-14-15-19-36-30(25-17-18-26(32)27(22-25)33-4)23(3)37-31-28(34-5)20-24(16-8-2)21-29(31)35-6/h8,17-18,20-23,30,32H,2,7,9-16,19H2,1,3-6H3
KEGG

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Article
PubMed
n/an/an/an/a 66n/an/an/an/a



Kansei Science Research and Biological Science Research, Kao Corporation, 2606 Akabane, Ichikai-Machi, Haga-Gun, Tochigi 321-3497, Japan.

Curated by ChEMBL


Assay Description
Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...

ACS Med Chem Lett 8: 715-719 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00104
BindingDB Entry DOI: 10.7270/Q2CZ39N2
More data for this
Ligand-Target Pair