BDBM50269845 CHEMBL4077630

SMILES: Oc1ccc(cc1)[C@H]1[C@@H]([C@@H]([C@H]1c1cc(O)cc(=O)o1)c1ccc(O)cc1)c1cc(O)cc(=O)o1

InChI Key: InChIKey=RYRAFHXNXUPLCM-KKLUKGEUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50269845 (CHEMBL4077630) Show SMILES Oc1ccc(cc1)[C@H]1[C@@H]([C@@H]([C@H]1c1cc(O)cc(=O)o1)c1ccc(O)cc1)c1cc(O)cc(=O)o1 |r| Show InChI InChI=1S/C26H20O8/c27-15-5-1-13(2-6-15)23-25(19-9-17(29)11-21(31)33-19)24(14-3-7-16(28)8-4-14)26(23)20-10-18(30)12-22(32)34-20/h1-12,23-30H/t23-,24-,25-,26-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...				Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50269845 (CHEMBL4077630) Show SMILES Oc1ccc(cc1)[C@H]1[C@@H]([C@@H]([C@H]1c1cc(O)cc(=O)o1)c1ccc(O)cc1)c1cc(O)cc(=O)o1 |r| Show InChI InChI=1S/C26H20O8/c27-15-5-1-13(2-6-15)23-25(19-9-17(29)11-21(31)33-19)24(14-3-7-16(28)8-4-14)26(23)20-10-18(30)12-22(32)34-20/h1-12,23-30H/t23-,24-,25-,26-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith Institute for Drug Discovery, Griffith University, Brisbane QLD 4111, Australia. Curated by ChEMBL					Assay Description Inhibition of Tdp1 (unknown origin) using 5'-(6-TAMN-AGGATCTAAAAGACTT-BHQ-)3' as substrate pretreated for 30 mins followed by substrate addition by f...				Bioorg Med Chem Lett 27: 4007-4010 (2017) Article DOI: 10.1016/j.bmcl.2017.07.062 BindingDB Entry DOI: 10.7270/Q2765HTQ
					More data for this Ligand-Target Pair