BindingDB logo
myBDB logout

null

SMILES: C1CC(CCN1)Oc1nccc(n1)-c1cnc2ccccn12

InChI Key: InChIKey=LRUYYHYHACYRQS-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50271562   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))		BDBM50271562
PNG
(3-(2-(piperidin-4-yloxy)pyrimidin-4-yl)H-imidazo[1...)
Show SMILES C1CC(CCN1)Oc1nccc(n1)-c1cnc2ccccn12
Show InChI InChI=1S/C16H17N5O/c1-2-10-21-14(11-19-15(21)3-1)13-6-9-18-16(20-13)22-12-4-7-17-8-5-12/h1-3,6,9-12,17H,4-5,7-8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.19E+3n/an/an/an/an/an/a



UCB

Curated by ChEMBL


Assay Description
Inhibition of IRAK4 (unknown origin)

Bioorg Med Chem Lett 18: 3291-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.039
BindingDB Entry DOI: 10.7270/Q2NZ87FX
More data for this
Ligand-Target Pair