null

SMILES: C1CC(CCN1)Nc1cccc(n1)-c1n[nH]c2ccccc12

InChI Key: InChIKey=JIVKWFIJGHPRQL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM50271602 (6-(1H-indazol-3-yl)-N-(piperidin-4-yl)pyridin-2-am...) Show SMILES C1CC(CCN1)Nc1cccc(n1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C17H19N5/c1-2-5-14-13(4-1)17(22-21-14)15-6-3-7-16(20-15)19-12-8-10-18-11-9-12/h1-7,12,18H,8-11H2,(H,19,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	456	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of IRAK4 (unknown origin)				Bioorg Med Chem Lett 18: 3291-5 (2008) Article DOI: 10.1016/j.bmcl.2008.04.039 BindingDB Entry DOI: 10.7270/Q2NZ87FX
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50271602 (6-(1H-indazol-3-yl)-N-(piperidin-4-yl)pyridin-2-am...) Show SMILES C1CC(CCN1)Nc1cccc(n1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C17H19N5/c1-2-5-14-13(4-1)17(22-21-14)15-6-3-7-16(20-15)19-12-8-10-18-11-9-12/h1-7,12,18H,8-11H2,(H,19,20)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of JNK2 (unknown origin)				Bioorg Med Chem Lett 18: 3291-5 (2008) Article DOI: 10.1016/j.bmcl.2008.04.039 BindingDB Entry DOI: 10.7270/Q2NZ87FX
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50271602 (6-(1H-indazol-3-yl)-N-(piperidin-4-yl)pyridin-2-am...) Show SMILES C1CC(CCN1)Nc1cccc(n1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C17H19N5/c1-2-5-14-13(4-1)17(22-21-14)15-6-3-7-16(20-15)19-12-8-10-18-11-9-12/h1-7,12,18H,8-11H2,(H,19,20)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin)				Bioorg Med Chem Lett 18: 3291-5 (2008) Article DOI: 10.1016/j.bmcl.2008.04.039 BindingDB Entry DOI: 10.7270/Q2NZ87FX
					More data for this Ligand-Target Pair