BDBM50272101 (E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[2,1-b]thiazole::CHEMBL505610

SMILES: C(=C/c1ccncn1)\c1c(nc2sccn12)-c1ccccc1

InChI Key: InChIKey=MRJKXXDKYLGLRQ-VOTSOKGWSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50272101 ((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...) Show SMILES C(=C/c1ccncn1)\c1c(nc2sccn12)-c1ccccc1 Show InChI InChI=1S/C17H12N4S/c1-2-4-13(5-3-1)16-15(21-10-11-22-17(21)20-16)7-6-14-8-9-18-12-19-14/h1-12H/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 system				Bioorg Med Chem Lett 18: 4723-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.106 BindingDB Entry DOI: 10.7270/Q2SJ1KD2
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50272101 ((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...) Show SMILES C(=C/c1ccncn1)\c1c(nc2sccn12)-c1ccccc1 Show InChI InChI=1S/C17H12N4S/c1-2-4-13(5-3-1)16-15(21-10-11-22-17(21)20-16)7-6-14-8-9-18-12-19-14/h1-12H/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 system				Bioorg Med Chem Lett 18: 4723-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.106 BindingDB Entry DOI: 10.7270/Q2SJ1KD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50272101 ((E/Z)-6-phenyl-5-(2-(pyrimidin-4-yl)vinyl)imidazo[...) Show SMILES C(=C/c1ccncn1)\c1c(nc2sccn12)-c1ccccc1 Show InChI InChI=1S/C17H12N4S/c1-2-4-13(5-3-1)16-15(21-10-11-22-17(21)20-16)7-6-14-8-9-18-12-19-14/h1-12H/b7-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 system				Bioorg Med Chem Lett 18: 4723-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.106 BindingDB Entry DOI: 10.7270/Q2SJ1KD2
					More data for this Ligand-Target Pair