BDBM50272154 1-(1-(4'-Fluorobiphenyl-4-yl)allyl)-1H-imidazole::CHEMBL500140

SMILES: Fc1ccc(cc1)-c1ccc(cc1)C(C=C)n1ccnc1

InChI Key: InChIKey=RIRIQVYCUKFYLC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM50272154 (1-(1-(4'-Fluorobiphenyl-4-yl)allyl)-1H-imidazole |...) Show SMILES Fc1ccc(cc1)-c1ccc(cc1)C(C=C)n1ccnc1 Show InChI InChI=1S/C18H15FN2/c1-2-18(21-12-11-20-13-21)16-5-3-14(4-6-16)15-7-9-17(19)10-8-15/h2-13,18H,1H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductase				Bioorg Med Chem 16: 7715-27 (2008) Article DOI: 10.1016/j.bmc.2008.07.011 BindingDB Entry DOI: 10.7270/Q2222TK7
					More data for this Ligand-Target Pair