BDBM50273028 (E)-2-(5-Fluoro-1-(naphthalen-2-ylmethylene)-1H-inden-3-yl)-ethanoic acid::CHEMBL515823

SMILES: OC(=O)CC1=C\C(=C/c2ccc3ccccc3c2)c2ccc(F)cc12

InChI Key: InChIKey=BLDZBZMGSVOARQ-LICLKQGHSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50273028 ((E)-2-(5-Fluoro-1-(naphthalen-2-ylmethylene)-1H-in...) Show SMILES OC(=O)CC1=C\C(=C/c2ccc3ccccc3c2)c2ccc(F)cc12 |t:4| Show InChI InChI=1S/C22H15FO2/c23-19-7-8-20-17(11-18(12-22(24)25)21(20)13-19)10-14-5-6-15-3-1-2-4-16(15)9-14/h1-11,13H,12H2,(H,24,25)/b17-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Vanderbilt University Center for Structural Biology Curated by ChEMBL					Assay Description Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...				J Med Chem 51: 4911-9 (2008) Article DOI: 10.1021/jm700969c BindingDB Entry DOI: 10.7270/Q2H70FM4
					More data for this Ligand-Target Pair