BindingDB PrimarySearch

BDBM50273358 (S)-N-((S)-6-amino-1-((S)-6-amino-1-((S)-1-((S)-1,6-diamino-1-oxohexan-2-ylamino)-1-oxo-6-palmitamidohexan-2-ylamino)-1-oxohexan-2-ylamino)-1-oxohexan-2-yl)-1-(2-((S)-2-((S)-2-((S)-2-(2-((S)-2-((S)-2-((S)-4-amino-2-((S)-2-((2S,3R)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-3-hydroxybutanamido)-4-methylpentanamido)-4-oxobutanamido)-3-hydroxypropanamido)propanamido)acetamido)-3-(4-hydroxyphenyl)propanamido)-4-methylpentanamido)-4-methylpentanamido)acetyl)pyrrolidine-2-carboxamide::CHEMBL506495::Gal-B5

SMILES: CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key: InChIKey=CYRNKOJFIDMNMV-WCXAHCKYSA-N

Data: 4 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50273358
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Galanin receptor 2 (Homo sapiens (Human))	BDBM50273358 ((S)-N-((S)-6-amino-1-((S)-6-amino-1-((S)-1-((S)-1,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Displacement of europium-labeled galanin from human GalR2 expressed in CHO-K1 cells				J Med Chem 51: 8038-47 (2008) Article DOI: 10.1021/jm801088x BindingDB Entry DOI: 10.7270/Q22B8ZXD
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Galanin receptor 2 (Homo sapiens (Human))	BDBM50273358 ((S)-N-((S)-6-amino-1-((S)-6-amino-1-((S)-1-((S)-1,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Displacement of Eu-labeled galanin from human GalR2 by DELFIA competitive assay				J Med Chem 53: 1871-5 (2010) Article DOI: 10.1021/jm9018349 BindingDB Entry DOI: 10.7270/Q26D5TXJ
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
GALR1 (Homo sapiens (Human))	BDBM50273358 ((S)-N-((S)-6-amino-1-((S)-6-amino-1-((S)-1-((S)-1,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	387	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Displacement of europium-labeled galanin from human GalR1 expressed in HEK293 EBNA cells				J Med Chem 51: 8038-47 (2008) Article DOI: 10.1021/jm801088x BindingDB Entry DOI: 10.7270/Q22B8ZXD
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
GALR1 (Homo sapiens (Human))	BDBM50273358 ((S)-N-((S)-6-amino-1-((S)-6-amino-1-((S)-1-((S)-1,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	387	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Displacement of Eu-labeled galanin from human GalR1 by DELFIA competitive assay				J Med Chem 53: 1871-5 (2010) Article DOI: 10.1021/jm9018349 BindingDB Entry DOI: 10.7270/Q26D5TXJ
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair