BDBM50273715 CHEMBL457069::[2-(Pyrazol-1-yl)ethyl]-bisphosphonic acid

SMILES: OP(O)(=O)C(Cn1cccn1)P(O)(O)=O

InChI Key: InChIKey=UUGUSMHQBIUYKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl diphosphate synthase (Homo sapiens (Human))	BDBM50273715 (CHEMBL457069 | [2-(Pyrazol-1-yl)ethyl]-bisphosphon...) Show SMILES OP(O)(=O)C(Cn1cccn1)P(O)(O)=O Show InChI InChI=1S/C5H10N2O6P2/c8-14(9,10)5(15(11,12)13)4-7-3-1-2-6-7/h1-3,5H,4H2,(H2,8,9,10)(H2,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Ferrara Curated by ChEMBL					Assay Description Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)				J Med Chem 51: 6800-7 (2008) Article DOI: 10.1021/jm801003y BindingDB Entry DOI: 10.7270/Q2F76CD8
					More data for this Ligand-Target Pair