BDBM50277605 CHEMBL4162781

SMILES: COc1ccc(Nc2nccc(n2)-c2sc(OC(C)C)nc2C)c(OC)c1

InChI Key: InChIKey=DIRQMALASQRMOQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277605 (CHEMBL4162781) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(OC(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C19H22N4O3S/c1-11(2)26-19-21-12(3)17(27-19)15-8-9-20-18(23-15)22-14-7-6-13(24-4)10-16(14)25-5/h6-11H,1-5H3,(H,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277605 (CHEMBL4162781) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(OC(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C19H22N4O3S/c1-11(2)26-19-21-12(3)17(27-19)15-8-9-20-18(23-15)22-14-7-6-13(24-4)10-16(14)25-5/h6-11H,1-5H3,(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair