BDBM50278147 CHEMBL513769::N-(2,4-dichlorobenzyl)-1-(2-fluorophenylsulfonyl)piperidine-4-carboxamide

SMILES: Fc1ccccc1S(=O)(=O)N1CCC(CC1)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key: InChIKey=XXDMCRHQQXNERV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50278147 (CHEMBL513769 | N-(2,4-dichlorobenzyl)-1-(2-fluorop...) Show SMILES Fc1ccccc1S(=O)(=O)N1CCC(CC1)C(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H19Cl2FN2O3S/c20-15-6-5-14(16(21)11-15)12-23-19(25)13-7-9-24(10-8-13)28(26,27)18-4-2-1-3-17(18)22/h1-6,11,13H,7-10,12H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	87.6	n/a	n/a	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase (unknown origin)				Bioorg Med Chem Lett 19: 2354-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.066 BindingDB Entry DOI: 10.7270/Q2J10322
					More data for this Ligand-Target Pair