BDBM50279540 4-(4-Fluoro-phenyl)-2-{4-[4-(1H-indol-3-yl)-piperidin-1-yl]-butyl}-pyrido[1,2-c]pyrimidine-1,3-dione::CHEMBL484980

SMILES: Fc1ccc(cc1)-c1c2ccccn2c(=O)n(CCCCN2CCC(CC2)c2c[nH]c3ccccc23)c1=O

InChI Key: InChIKey=DULILSLOYROQDS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50279540 (4-(4-Fluoro-phenyl)-2-{4-[4-(1H-indol-3-yl)-piperi...) Show SMILES Fc1ccc(cc1)-c1c2ccccn2c(=O)n(CCCCN2CCC(CC2)c2c[nH]c3ccccc23)c1=O Show InChI InChI=1S/C31H31FN4O2/c32-24-12-10-23(11-13-24)29-28-9-3-4-17-35(28)31(38)36(30(29)37)18-6-5-16-34-19-14-22(15-20-34)26-21-33-27-8-2-1-7-25(26)27/h1-4,7-13,17,21-22,33H,5-6,14-16,18-20H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Warsaw Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat brain membranes				Eur J Med Chem 44: 1710-7 (2009) Article DOI: 10.1016/j.ejmech.2008.09.021 BindingDB Entry DOI: 10.7270/Q22N5249
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50279540 (4-(4-Fluoro-phenyl)-2-{4-[4-(1H-indol-3-yl)-piperi...) Show SMILES Fc1ccc(cc1)-c1c2ccccn2c(=O)n(CCCCN2CCC(CC2)c2c[nH]c3ccccc23)c1=O Show InChI InChI=1S/C31H31FN4O2/c32-24-12-10-23(11-13-24)29-28-9-3-4-17-35(28)31(38)36(30(29)37)18-6-5-16-34-19-14-22(15-20-34)26-21-33-27-8-2-1-7-25(26)27/h1-4,7-13,17,21-22,33H,5-6,14-16,18-20H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Warsaw Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from 5HTT in rat brain membranes				Eur J Med Chem 44: 1710-7 (2009) Article DOI: 10.1016/j.ejmech.2008.09.021 BindingDB Entry DOI: 10.7270/Q22N5249
					More data for this Ligand-Target Pair