BindingDB logo
myBDB logout

BDBM50279865 (6E,8E,10E,14Z)-(5S,12R)-5-Hydroxy-12-methyl-icosa-6,8,10,14-tetraenoic acid::CHEMBL53967

SMILES: CCCCC\C=C/C[C@@H](C)\C=C\C=C\C=C\[C@@H](O)CCCC(O)=O

InChI Key: InChIKey=CJHXJQVOZSVURY-XWRXVLDRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279865   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50279865
PNG
((6E,8E,10E,14Z)-(5S,12R)-5-Hydroxy-12-methyl-icosa...)
Show SMILES CCCCC\C=C/C[C@@H](C)\C=C\C=C\C=C\[C@@H](O)CCCC(O)=O
Show InChI InChI=1S/C21H34O3/c1-3-4-5-6-7-10-14-19(2)15-11-8-9-12-16-20(22)17-13-18-21(23)24/h7-12,15-16,19-20,22H,3-6,13-14,17-18H2,1-2H3,(H,23,24)/b9-8+,10-7-,15-11+,16-12+/t19-,20-/m1/s1
PDB

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 3.80E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itself


Bioorg Med Chem Lett 1: 179-182 (1991)


Article DOI: 10.1016/S0960-894X(01)80795-2
BindingDB Entry DOI: 10.7270/Q2N016DR
More data for this
Ligand-Target Pair