BDBM50280051 5-[2-(3-Trifluoromethyl-phenylamino)-pyridin-3-yl]-3H-[1,3,4]oxadiazole-2-thione::CHEMBL350729

SMILES: FC(F)(F)c1cccc(Nc2ncccc2-c2nnc(S)o2)c1

InChI Key: InChIKey=XLDVKDDECYUBSO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (RAT)	BDBM50280051 (5-[2-(3-Trifluoromethyl-phenylamino)-pyridin-3-yl]...) Show SMILES FC(F)(F)c1cccc(Nc2ncccc2-c2nnc(S)o2)c1 Show InChI InChI=1S/C14H9F3N4OS/c15-14(16,17)8-3-1-4-9(7-8)19-11-10(5-2-6-18-11)12-20-21-13(23)22-12/h1-7H,(H,18,19)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Cyclooxygenase was determined				Bioorg Med Chem Lett 2: 69-72 (1992) Article DOI: 10.1016/S0960-894X(00)80657-5 BindingDB Entry DOI: 10.7270/Q29K4B4Q
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50280051 (5-[2-(3-Trifluoromethyl-phenylamino)-pyridin-3-yl]...) Show SMILES FC(F)(F)c1cccc(Nc2ncccc2-c2nnc(S)o2)c1 Show InChI InChI=1S/C14H9F3N4OS/c15-14(16,17)8-3-1-4-9(7-8)19-11-10(5-2-6-18-11)12-20-21-13(23)22-12/h1-7H,(H,18,19)(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against 5-lipoxygenase was determined				Bioorg Med Chem Lett 2: 69-72 (1992) Article DOI: 10.1016/S0960-894X(00)80657-5 BindingDB Entry DOI: 10.7270/Q29K4B4Q
					More data for this Ligand-Target Pair