BDBM50280310 8-Ethyl-3-phenyl-8H-1,2,3a,7,8,9-hexaaza-dibenzo[e,h]azulene::CHEMBL52149

SMILES: CCN1c2ncccc2-c2nnc(-c3ccccc3)n2-c2cccnc12

InChI Key: InChIKey=LPFALGFUSUWWTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50280310 (8-Ethyl-3-phenyl-8H-1,2,3a,7,8,9-hexaaza-dibenzo[e...) Show SMILES CCN1c2ncccc2-c2nnc(-c3ccccc3)n2-c2cccnc12 Show InChI InChI=1S/C20H16N6/c1-2-25-18-15(10-6-12-21-18)19-24-23-17(14-8-4-3-5-9-14)26(19)16-11-7-13-22-20(16)25/h3-13H,2H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit HIV-1 IIIB reverse transcriptase catalyzed incorporation of tritiated thymidine triphosphate onto a biotinylated rA.dT template pr...				Bioorg Med Chem Lett 2: 1745-1750 (1992) Article DOI: 10.1016/S0960-894X(00)80468-0 BindingDB Entry DOI: 10.7270/Q2X63MW9
					More data for this Ligand-Target Pair