BDBM50280331 CHEMBL49192::[9-Oxo-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-8-aza-spiro[4.5]dec-(7E)-ylidene]-acetic acid ethyl ester

SMILES: CCOC(=O)\C=C1/CC2(CCCC2)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=OAAZBZKVGLHRJX-RCCKNPSSSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50280331 (CHEMBL49192 | [9-Oxo-8-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCOC(=O)\C=C1/CC2(CCCC2)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C27H29N5O3/c1-2-35-25(34)15-21-16-27(13-5-6-14-27)17-24(33)32(21)18-19-9-11-20(12-10-19)22-7-3-4-8-23(22)26-28-30-31-29-26/h3-4,7-12,15H,2,5-6,13-14,16-18H2,1H3,(H,28,29,30,31)/b21-15+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity against Angiotensin II receptor in rabbit aorta rings				Bioorg Med Chem Lett 4: 87-92 (1994) Article DOI: 10.1016/S0960-894X(01)81127-6 BindingDB Entry DOI: 10.7270/Q2BC40QF
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280331 (CHEMBL49192 | [9-Oxo-8-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCOC(=O)\C=C1/CC2(CCCC2)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C27H29N5O3/c1-2-35-25(34)15-21-16-27(13-5-6-14-27)17-24(33)32(21)18-19-9-11-20(12-10-19)22-7-3-4-8-23(22)26-28-30-31-29-26/h3-4,7-12,15H,2,5-6,13-14,16-18H2,1H3,(H,28,29,30,31)/b21-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair