BDBM50280512 5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one::CHEMBL162840

SMILES: Cc1ccc(Cl)c(Nc2ccccc2C=C2SC(S)=NC2=O)c1Cl

InChI Key: InChIKey=VFHQMOPQDPVAMG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (RAT)	BDBM50280512 (5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C=C2SC(S)=NC2=O)c1Cl |w:14.14,c:19| Show InChI InChI=1S/C17H12Cl2N2OS2/c1-9-6-7-11(18)15(14(9)19)20-12-5-3-2-4-10(12)8-13-16(22)21-17(23)24-13/h2-8,20H,1H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)				Bioorg Med Chem Lett 2: 705-708 (1992) Article DOI: 10.1016/S0960-894X(00)80396-0 BindingDB Entry DOI: 10.7270/Q26H4HBV
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50280512 (5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C=C2SC(S)=NC2=O)c1Cl |w:14.14,c:19| Show InChI InChI=1S/C17H12Cl2N2OS2/c1-9-6-7-11(18)15(14(9)19)20-12-5-3-2-4-10(12)8-13-16(22)21-17(23)24-13/h2-8,20H,1H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase)				Bioorg Med Chem Lett 2: 705-708 (1992) Article DOI: 10.1016/S0960-894X(00)80396-0 BindingDB Entry DOI: 10.7270/Q26H4HBV
					More data for this Ligand-Target Pair