BDBM50281272 (2R,3S)-5-(2-Dimethylamino-ethyl)-8-methoxy-2-(4-methoxy-phenyl)-3-methyl-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one::CHEMBL96454

SMILES: COc1ccc(cc1)[C@@H]1Sc2cc(OC)ccc2N(CCN(C)C)C(=O)[C@@H]1C

InChI Key: InChIKey=CTODIDSYHUNZEK-QVKFZJNVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated L-type calcium channel (Homo sapiens (Human))	BDBM50281272 ((2R,3S)-5-(2-Dimethylamino-ethyl)-8-methoxy-2-(4-m...) Show SMILES COc1ccc(cc1)[C@@H]1Sc2cc(OC)ccc2N(CCN(C)C)C(=O)[C@@H]1C Show InChI InChI=1S/C22H28N2O3S/c1-15-21(16-6-8-17(26-4)9-7-16)28-20-14-18(27-5)10-11-19(20)24(22(15)25)13-12-23(2)3/h6-11,14-15,21H,12-13H2,1-5H3/t15-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscle				Bioorg Med Chem Lett 3: 2797-2800 (1993) Article DOI: 10.1016/S0960-894X(01)80767-8 BindingDB Entry DOI: 10.7270/Q2FN164V
					More data for this Ligand-Target Pair