BDBM50281710 (R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one::CHEMBL171531

SMILES: CN1c2ccccc2C(=N[C@@H](N)C1=O)c1ccccc1

InChI Key: InChIKey=MWASGDJOVNIDEM-OAHLLOKOSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50281710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281710 ((R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e]...) Show SMILES CN1c2ccccc2C(=N[C@@H](N)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C16H15N3O/c1-19-13-10-6-5-9-12(13)14(18-15(17)16(19)20)11-7-3-2-4-8-11/h2-10,15H,17H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its activity to inhibit the binding of [125I]-CCK-33 to Cholecystokinin type B receptor in guinea pig brain				Bioorg Med Chem Lett 3: 867-870 (1993) Article DOI: 10.1016/S0960-894X(00)80682-4 BindingDB Entry DOI: 10.7270/Q28S4PTK
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50281710 ((R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e]...) Show SMILES CN1c2ccccc2C(=N[C@@H](N)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C16H15N3O/c1-19-13-10-6-5-9-12(13)14(18-15(17)16(19)20)11-7-3-2-4-8-11/h2-10,15H,17H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its activity to inhibit the binding of [125I]-CCK-33 to Cholecystokinin type A receptor in rat pancreas				Bioorg Med Chem Lett 3: 867-870 (1993) Article DOI: 10.1016/S0960-894X(00)80682-4 BindingDB Entry DOI: 10.7270/Q28S4PTK
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281710 ((R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e]...) Show SMILES CN1c2ccccc2C(=N[C@@H](N)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C16H15N3O/c1-19-13-10-6-5-9-12(13)14(18-15(17)16(19)20)11-7-3-2-4-8-11/h2-10,15H,17H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its activity to inhibit the binding of [125I]-gastrin to gastric glands (gastrin) in guinea pig				Bioorg Med Chem Lett 3: 867-870 (1993) Article DOI: 10.1016/S0960-894X(00)80682-4 BindingDB Entry DOI: 10.7270/Q28S4PTK
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50281710 ((R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e]...) Show SMILES CN1c2ccccc2C(=N[C@@H](N)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C16H15N3O/c1-19-13-10-6-5-9-12(13)14(18-15(17)16(19)20)11-7-3-2-4-8-11/h2-10,15H,17H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissue				J Med Chem 31: 2235-46 (1989) BindingDB Entry DOI: 10.7270/Q2PG1S9K
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281710 ((R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e]...) Show SMILES CN1c2ccccc2C(=N[C@@H](N)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C16H15N3O/c1-19-13-10-6-5-9-12(13)14(18-15(17)16(19)20)11-7-3-2-4-8-11/h2-10,15H,17H2,1H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissue				J Med Chem 31: 2235-46 (1989) BindingDB Entry DOI: 10.7270/Q2PG1S9K
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281710 ((R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e]...) Show SMILES CN1c2ccccc2C(=N[C@@H](N)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C16H15N3O/c1-19-13-10-6-5-9-12(13)14(18-15(17)16(19)20)11-7-3-2-4-8-11/h2-10,15H,17H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glands				J Med Chem 31: 2235-46 (1989) BindingDB Entry DOI: 10.7270/Q2PG1S9K
					More data for this Ligand-Target Pair