BDBM50282412 2-Butyl-3-(2'-tetrazol-1-yl-biphenyl-4-ylmethyl)-3H-imidazole-4-carboxylic acid::CHEMBL349389
SMILES: CCCCc1ncc(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-n1cnnn1
InChI Key: InChIKey=OYTARQUBYJLZTG-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin II AT2 (RAT) | BDBM50282412 (2-Butyl-3-(2'-tetrazol-1-yl-biphenyl-4-ylmethyl)-3...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin II (AT2) receptor to displace 125I-Sar,Ile8-AII in rat midbrain | Bioorg Med Chem Lett 4: 69-74 (1994) Article DOI: 10.1016/S0960-894X(01)81124-0 BindingDB Entry DOI: 10.7270/Q2NS0TVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin II type 1a (AT-1a) receptor (RABBIT) | BDBM50282412 (2-Butyl-3-(2'-tetrazol-1-yl-biphenyl-4-ylmethyl)-3...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 1 to displace 125I-Sar,Ile8-AII in rabbit aorta | Bioorg Med Chem Lett 4: 69-74 (1994) Article DOI: 10.1016/S0960-894X(01)81124-0 BindingDB Entry DOI: 10.7270/Q2NS0TVK | |||||||||||
More data for this Ligand-Target Pair |