BDBM50282456 CHEMBL169827::N-[3-(2'-Benzoylsulfamoyl-biphenyl-4-ylmethyl)-2-ethyl-4-oxo-3,4-dihydro-quinazolin-6-yl]-N-benzyl-benzamide

SMILES: CCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1)N(Cc1ccccc1)C(=O)c1ccccc1

InChI Key: InChIKey=UIRITQOIXTYBEJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50282456 (CHEMBL169827 | N-[3-(2'-Benzoylsulfamoyl-biphenyl-...) Show SMILES CCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1)N(Cc1ccccc1)C(=O)c1ccccc1 Show InChI InChI=1S/C44H36N4O5S/c1-2-41-45-39-27-26-36(47(29-31-14-6-3-7-15-31)43(50)35-18-10-5-11-19-35)28-38(39)44(51)48(41)30-32-22-24-33(25-23-32)37-20-12-13-21-40(37)54(52,53)46-42(49)34-16-8-4-9-17-34/h3-28H,2,29-30H2,1H3,(H,46,49)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for binding affinity against angiotensin II receptor type 2 in rat midbrain membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50282456 (CHEMBL169827 | N-[3-(2'-Benzoylsulfamoyl-biphenyl-...) Show SMILES CCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1)N(Cc1ccccc1)C(=O)c1ccccc1 Show InChI InChI=1S/C44H36N4O5S/c1-2-41-45-39-27-26-36(47(29-31-14-6-3-7-15-31)43(50)35-18-10-5-11-19-35)28-38(39)44(51)48(41)30-32-22-24-33(25-23-32)37-20-12-13-21-40(37)54(52,53)46-42(49)34-16-8-4-9-17-34/h3-28H,2,29-30H2,1H3,(H,46,49)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair