BDBM50283112 5,5-Diphenyl-3-[2-(4-phenyl-piperidin-1-yl)-ethyl]-imidazolidine-2,4-dione::CHEMBL308433
SMILES: O=C1NC(C(=O)N1CCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1
InChI Key: InChIKey=RCILDDKJWKDONY-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50283112 (5,5-Diphenyl-3-[2-(4-phenyl-piperidin-1-yl)-ethyl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT | Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50283112 (5,5-Diphenyl-3-[2-(4-phenyl-piperidin-1-yl)-ethyl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG | Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266 | |||||||||||
More data for this Ligand-Target Pair |