BDBM50283631 (S)-2-[(S)-3-Benzo[1,3]dioxol-5-yl-2-(phosphonomethyl-amino)-propionylamino]-3-biphenyl-4-yl-propionic acid::CHEMBL328463

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccc2OCOc2c1)NCP(O)(O)=O

InChI Key: InChIKey=RZJKWVPUWYLTJN-VXKWHMMOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283631 ((S)-2-[(S)-3-Benzo[1,3]dioxol-5-yl-2-(phosphonomet...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccc2OCOc2c1)NCP(O)(O)=O Show InChI InChI=1S/C26H27N2O8P/c29-25(21(27-15-37(32,33)34)13-18-8-11-23-24(14-18)36-16-35-23)28-22(26(30)31)12-17-6-9-20(10-7-17)19-4-2-1-3-5-19/h1-11,14,21-22,27H,12-13,15-16H2,(H,28,29)(H,30,31)(H2,32,33,34)/t21-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283631 ((S)-2-[(S)-3-Benzo[1,3]dioxol-5-yl-2-(phosphonomet...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccc2OCOc2c1)NCP(O)(O)=O Show InChI InChI=1S/C26H27N2O8P/c29-25(21(27-15-37(32,33)34)13-18-8-11-23-24(14-18)36-16-35-23)28-22(26(30)31)12-17-6-9-20(10-7-17)19-4-2-1-3-5-19/h1-11,14,21-22,27H,12-13,15-16H2,(H,28,29)(H,30,31)(H2,32,33,34)/t21-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair