BDBM50283736 (S)-2-[5-((R)-2-Amino-3-mercapto-propionylamino)-2-(4-fluoro-benzyl)-pentanoylamino]-4-methylsulfanyl-butyric acid::CHEMBL96413

SMILES: CSCC[C@H](NC(=O)C(CCCNC(=O)[C@@H](N)CS)Cc1ccc(F)cc1)C(O)=O

InChI Key: InChIKey=QMBOMETUAPMBFM-HGVHAKBWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283736 ((S)-2-[5-((R)-2-Amino-3-mercapto-propionylamino)-2...) Show SMILES CSCC[C@H](NC(=O)C(CCCNC(=O)[C@@H](N)CS)Cc1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C20H30FN3O4S2/c1-30-10-8-17(20(27)28)24-18(25)14(11-13-4-6-15(21)7-5-13)3-2-9-23-19(26)16(22)12-29/h4-7,14,16-17,29H,2-3,8-12,22H2,1H3,(H,23,26)(H,24,25)(H,27,28)/t14?,16-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against geranylgeranyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283736 ((S)-2-[5-((R)-2-Amino-3-mercapto-propionylamino)-2...) Show SMILES CSCC[C@H](NC(=O)C(CCCNC(=O)[C@@H](N)CS)Cc1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C20H30FN3O4S2/c1-30-10-8-17(20(27)28)24-18(25)14(11-13-4-6-15(21)7-5-13)3-2-9-23-19(26)16(22)12-29/h4-7,14,16-17,29H,2-3,8-12,22H2,1H3,(H,23,26)(H,24,25)(H,27,28)/t14?,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair