BDBM50284086 CHEMBL161811::Trifluoro-methanesulfonic acid (5S,6R)-6-dipropylamino-5-methyl-5,6,7,8-tetrahydro-naphthalen-1-yl ester

SMILES: CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C

InChI Key: InChIKey=MUVDWLPPMXZXRR-XJKSGUPXSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50284086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50284086 (CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50284086 (CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50284086 (CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	546	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50284086 (CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
					More data for this Ligand-Target Pair