BDBM50284448 CHEMBL280290::[2,6-Dichloro-4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-phenyl-acetic acid

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(O)=O)c2ccccc2)c(Cl)c1

InChI Key: InChIKey=XGJGGEIDHKFIRB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50284448 (CHEMBL280290 | [2,6-Dichloro-4-(2-ethyl-5,7-dimeth...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(O)=O)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C25H23Cl2N3O3/c1-4-20-29-21-14(2)10-15(3)28-24(21)30(20)13-16-11-18(26)23(19(27)12-16)33-22(25(31)32)17-8-6-5-7-9-17/h5-12,22H,4,13H2,1-3H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rat midbrain membrane (AT2 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50284448 (CHEMBL280290 | [2,6-Dichloro-4-(2-ethyl-5,7-dimeth...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(O)=O)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C25H23Cl2N3O3/c1-4-20-29-21-14(2)10-15(3)28-24(21)30(20)13-16-11-18(26)23(19(27)12-16)33-22(25(31)32)17-8-6-5-7-9-17/h5-12,22H,4,13H2,1-3H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair