BDBM50284645 CHEMBL29512::N-Benzyl-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4-oxo-3,4-dihydro-quinazolin-6-yl}-benzamide

SMILES: Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2ccccc2)cc1

InChI Key: InChIKey=LAKKZSUSZAINIW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50284645 (CHEMBL29512 | N-Benzyl-N-{3-[2'-(1-methyl-1H-tetra...) Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H29N7O2/c1-42-35(39-40-41-42)32-15-9-8-14-31(32)28-18-16-27(17-19-28)23-43-25-38-34-21-20-30(22-33(34)37(43)46)44(24-26-10-4-2-5-11-26)36(45)29-12-6-3-7-13-29/h2-22,25H,23-24H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in rat adrenal tissue				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50284645 (CHEMBL29512 | N-Benzyl-N-{3-[2'-(1-methyl-1H-tetra...) Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H29N7O2/c1-42-35(39-40-41-42)32-15-9-8-14-31(32)28-18-16-27(17-19-28)23-43-25-38-34-21-20-30(22-33(34)37(43)46)44(24-26-10-4-2-5-11-26)36(45)29-12-6-3-7-13-29/h2-22,25H,23-24H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in rabbit aorta				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair