BDBM50284663 CHEMBL282168::N-Butyl-4-hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4-oxo-3,4-dihydro-quinazolin-6-yl}-benzamide

SMILES: CCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1

InChI Key: InChIKey=AGAKGDNXFKHLQS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50284663 (CHEMBL282168 | N-Butyl-4-hydroxy-N-{3-[2'-(1-methy...) Show SMILES CCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H31N7O3/c1-3-4-19-41(33(43)25-13-16-27(42)17-14-25)26-15-18-31-30(20-26)34(44)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22,42H,3-4,19,21H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in rabbit aorta				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50284663 (CHEMBL282168 | N-Butyl-4-hydroxy-N-{3-[2'-(1-methy...) Show SMILES CCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H31N7O3/c1-3-4-19-41(33(43)25-13-16-27(42)17-14-25)26-15-18-31-30(20-26)34(44)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22,42H,3-4,19,21H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in rat adrenal tissue				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM50284663 (CHEMBL282168 | N-Butyl-4-hydroxy-N-{3-[2'-(1-methy...) Show SMILES CCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H31N7O3/c1-3-4-19-41(33(43)25-13-16-27(42)17-14-25)26-15-18-31-30(20-26)34(44)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22,42H,3-4,19,21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in human adrenal tissue				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair