BDBM50284671 CHEMBL29020::N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4-oxo-3,4-dihydro-quinazolin-6-yl}-N-pyridin-4-ylmethyl-benzamide

SMILES: Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccncc2)C(=O)c2ccccc2)cc1

InChI Key: InChIKey=HIGSLSHRNODNBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50284671 (CHEMBL29020 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...) Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccncc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-10-6-5-9-30(31)27-13-11-25(12-14-27)22-43-24-38-33-16-15-29(21-32(33)36(43)46)44(23-26-17-19-37-20-18-26)35(45)28-7-3-2-4-8-28/h2-21,24H,22-23H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in rabbit aorta				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
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