BDBM50284892 (1-{(R)-1-{3-[(E)-2-(5-Chloro-4-isopropyl-thiazol-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::CHEMBL297396

SMILES: CC(C)c1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)sc1Cl

InChI Key: InChIKey=FFDNDCRPDFIUAG-YZGDDWERSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284892 ((1-{(R)-1-{3-[(E)-2-(5-Chloro-4-isopropyl-thiazol-...) Show SMILES CC(C)c1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)sc1Cl Show InChI InChI=1S/C32H38ClNO3S2/c1-21(2)29-30(33)39-27(34-29)15-12-22-8-7-10-24(18-22)26(38-20-32(16-17-32)19-28(35)36)14-13-23-9-5-6-11-25(23)31(3,4)37/h5-12,15,18,21,26,37H,13-14,16-17,19-20H2,1-4H3,(H,35,36)/b15-12+/t26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284892 ((1-{(R)-1-{3-[(E)-2-(5-Chloro-4-isopropyl-thiazol-...) Show SMILES CC(C)c1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)sc1Cl Show InChI InChI=1S/C32H38ClNO3S2/c1-21(2)29-30(33)39-27(34-29)15-12-22-8-7-10-24(18-22)26(38-20-32(16-17-32)19-28(35)36)14-13-23-9-5-6-11-25(23)31(3,4)37/h5-12,15,18,21,26,37H,13-14,16-17,19-20H2,1-4H3,(H,35,36)/b15-12+/t26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair