BDBM50285427 Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulfanyl]-pentyl}-ethyl-amine::CHEMBL54032

SMILES: CCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1

InChI Key: InChIKey=ODOBCFFQEAXLPC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl coenzyme A:cholesterol acyltransferase 1 (Mus musculus)	BDBM50285427 (Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...) Show SMILES CCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1 Show InChI InChI=1S/C31H34N4O3S/c1-4-35(31-32-26-10-6-7-11-27(26)38-31)20-8-5-9-21-39-30-33-28(22-12-16-24(36-2)17-13-22)29(34-30)23-14-18-25(37-3)19-15-23/h6-7,10-19H,4-5,8-9,20-21H2,1-3H3,(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture				Bioorg Med Chem Lett 5: 177-180 (1995) Article DOI: 10.1016/0960-894X(95)00003-C BindingDB Entry DOI: 10.7270/Q2PG1RQJ
					More data for this Ligand-Target Pair
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50285427 (Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...) Show SMILES CCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1 Show InChI InChI=1S/C31H34N4O3S/c1-4-35(31-32-26-10-6-7-11-27(26)38-31)20-8-5-9-21-39-30-33-28(22-12-16-24(36-2)17-13-22)29(34-30)23-14-18-25(37-3)19-15-23/h6-7,10-19H,4-5,8-9,20-21H2,1-3H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assay				Bioorg Med Chem Lett 5: 177-180 (1995) Article DOI: 10.1016/0960-894X(95)00003-C BindingDB Entry DOI: 10.7270/Q2PG1RQJ
					More data for this Ligand-Target Pair