BDBM50285676 CHEMBL86302::[1-((R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyridin-5-yl)-vinyl]-phenyl}-3-phenyl-propylsulfanylmethyl)-cyclopropyl]-acetic acid

SMILES: OC(=O)CC1(CS[C@H](CCc2ccccc2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1

InChI Key: InChIKey=OSSGVJHRBLHMLQ-KMEWNKIWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50285676 (CHEMBL86302 | [1-((R)-1-{3-[(E)-2-(2,3-Dichloro-th...) Show SMILES OC(=O)CC1(CS[C@H](CCc2ccccc2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C30H27Cl2NO2S2/c31-27-28-25(37-29(27)32)14-12-23(33-28)11-9-21-7-4-8-22(17-21)24(13-10-20-5-2-1-3-6-20)36-19-30(15-16-30)18-26(34)35/h1-9,11-12,14,17,24H,10,13,15-16,18-19H2,(H,34,35)/b11-9+/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.63	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair