BDBM50285758 5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl urea analogue::CHEMBL315327

SMILES: CCCc1nc(SC)c(n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1)C(O)(CC)C(O)=O

InChI Key: InChIKey=VHKABADSXRJRMN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50285758 (5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...) Show SMILES CCCc1nc(SC)c(n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1)C(O)(CC)C(O)=O Show InChI InChI=1S/C32H36N4O6S2/c1-4-11-27-34-29(43-3)28(32(40,5-2)30(37)38)36(27)21-23-16-18-24(19-17-23)25-14-9-10-15-26(25)44(41,42)35-31(39)33-20-22-12-7-6-8-13-22/h6-10,12-19,40H,4-5,11,20-21H2,1-3H3,(H,37,38)(H2,33,35,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity at Angiotensin II Type 1 receptor in rat liver membrane by [125I]AII displacement.				Bioorg Med Chem Lett 5: 2611-2616 (1995) Article DOI: 10.1016/0960-894X(95)00479-D BindingDB Entry DOI: 10.7270/Q2GT5N57
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM50285758 (5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...) Show SMILES CCCc1nc(SC)c(n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1)C(O)(CC)C(O)=O Show InChI InChI=1S/C32H36N4O6S2/c1-4-11-27-34-29(43-3)28(32(40,5-2)30(37)38)36(27)21-23-16-18-24(19-17-23)25-14-9-10-15-26(25)44(41,42)35-31(39)33-20-22-12-7-6-8-13-22/h6-10,12-19,40H,4-5,11,20-21H2,1-3H3,(H,37,38)(H2,33,35,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity at Angiotensin II Type 2 receptor in rabbit uterus membrane by [125I]-AII displacement.				Bioorg Med Chem Lett 5: 2611-2616 (1995) Article DOI: 10.1016/0960-894X(95)00479-D BindingDB Entry DOI: 10.7270/Q2GT5N57
					More data for this Ligand-Target Pair