BDBM50285841 CHEMBL262383::Pseudopeptide derivative

SMILES: CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CN(CCSSCCN(CC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCSC)C(O)=O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(O)=O

InChI Key: InChIKey=TXXSJMWGQZWTQV-ZQWQDMLBSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50285841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50285841 (CHEMBL262383 | Pseudopeptide derivative) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CN(CCSSCCN(CC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCSC)C(O)=O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(O)=O Show InChI InChI=1S/C48H68N6O12S4/c1-47(2,3)65-45(63)51(29-39(55)53-27-33-15-11-9-13-31(33)25-37(53)41(57)49-35(43(59)60)17-21-67-7)19-23-69-70-24-20-52(46(64)66-48(4,5)6)30-40(56)54-28-34-16-12-10-14-32(34)26-38(54)42(58)50-36(44(61)62)18-22-68-8/h9-16,35-38H,17-30H2,1-8H3,(H,49,57)(H,50,58)(H,59,60)(H,61,62)/t35-,36-,37-,38-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50285841 (CHEMBL262383 | Pseudopeptide derivative) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CN(CCSSCCN(CC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCSC)C(O)=O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(O)=O Show InChI InChI=1S/C48H68N6O12S4/c1-47(2,3)65-45(63)51(29-39(55)53-27-33-15-11-9-13-31(33)25-37(53)41(57)49-35(43(59)60)17-21-67-7)19-23-69-70-24-20-52(46(64)66-48(4,5)6)30-40(56)54-28-34-16-12-10-14-32(34)26-38(54)42(58)50-36(44(61)62)18-22-68-8/h9-16,35-38H,17-30H2,1-8H3,(H,49,57)(H,50,58)(H,59,60)(H,61,62)/t35-,36-,37-,38-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibiion of bovine farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50285841 (CHEMBL262383 | Pseudopeptide derivative) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CN(CCSSCCN(CC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCSC)C(O)=O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(O)=O Show InChI InChI=1S/C48H68N6O12S4/c1-47(2,3)65-45(63)51(29-39(55)53-27-33-15-11-9-13-31(33)25-37(53)41(57)49-35(43(59)60)17-21-67-7)19-23-69-70-24-20-52(46(64)66-48(4,5)6)30-40(56)54-28-34-16-12-10-14-32(34)26-38(54)42(58)50-36(44(61)62)18-22-68-8/h9-16,35-38H,17-30H2,1-8H3,(H,49,57)(H,50,58)(H,59,60)(H,61,62)/t35-,36-,37-,38-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase in NIH3T3 cell based assay in non-reducing (-DTT) conditions				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair