BDBM50286941 5-(3,4-Difluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-tetrazole::CHEMBL366886

SMILES: CS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(F)c(F)c1

InChI Key: InChIKey=HUSJYWXNWVRFER-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50286941 (5-(3,4-Difluoro-phenyl)-1-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N4O2S/c1-23(21,22)11-5-3-10(4-6-11)20-14(17-18-19-20)9-2-7-12(15)13(16)8-9/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against human recombinant Prostaglandin G/H synthase 2 expressed in microsomes taken from baculovirus infected Sf...				Bioorg Med Chem Lett 6: 87-92 (1996) Article DOI: 10.1016/0960-894X(95)00564-A BindingDB Entry DOI: 10.7270/Q20C4VR4
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50286941 (5-(3,4-Difluoro-phenyl)-1-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N4O2S/c1-23(21,22)11-5-3-10(4-6-11)20-14(17-18-19-20)9-2-7-12(15)13(16)8-9/h2-8H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against human recombinant Prostaglandin G/H synthase 1 expressed in microsomes taken from baculovirus infected Sf...				Bioorg Med Chem Lett 6: 87-92 (1996) Article DOI: 10.1016/0960-894X(95)00564-A BindingDB Entry DOI: 10.7270/Q20C4VR4
					More data for this Ligand-Target Pair