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SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](-[#8])=O

InChI Key: InChIKey=UYQJMOHRDQCUAJ-FJNYLYSMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50287114 ((4E,8E)-2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-5,9,...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C27H37NO5/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-23(26(30)31)25(29)28-24(27(32)33)18-22-14-6-5-7-15-22/h5-7,10,12,14-16,23-24H,8-9,11,13,17-18H2,1-4H3,(H,28,29)(H,30,31)(H,32,33)/b20-12+,21-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl protein transferase from bovine brain				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50287114 ((4E,8E)-2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-5,9,...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C27H37NO5/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-23(26(30)31)25(29)28-24(27(32)33)18-22-14-6-5-7-15-22/h5-7,10,12,14-16,23-24H,8-9,11,13,17-18H2,1-4H3,(H,28,29)(H,30,31)(H,32,33)/b20-12+,21-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of squalene synthase from rat liver microsomes				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair