BDBM50288953 11'N-(3-bromobenzyl)spiro[dihydro[1,3]dioxolane-2,8'-pentacyclo[5.4.0.02,6.03,10.05,9]undecane]-11'-amine; hydrochloride::CHEMBL1190672::CHEMBL541347

SMILES: Brc1cccc(CNC2C3C4C5C3C3(OCCO3)C3C5CC4C23)c1

InChI Key: InChIKey=WAUBOCWMTBAXMK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50288953 (11'N-(3-bromobenzyl)spiro[dihydro[1,3]dioxolane-2,...) Show SMILES Brc1cccc(CNC2C3C4C5C3C3(OCCO3)C3C5CC4C23)c1 |TLB:13:18:11.10:20,8:22:11.10:20,THB:12:11:18.22:20,9:10:18.22:20| Show InChI InChI=1S/C20H22BrNO2/c21-10-3-1-2-9(6-10)8-22-19-15-11-7-12-14-13(11)16(19)18(14)20(17(12)15)23-4-5-24-20/h1-3,6,11-19,22H,4-5,7-8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligand				Bioorg Med Chem Lett 6: 595-600 (1996) Article DOI: 10.1016/0960-894X(96)00067-4 BindingDB Entry DOI: 10.7270/Q2GM87TV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50288953 (11'N-(3-bromobenzyl)spiro[dihydro[1,3]dioxolane-2,...) Show SMILES Brc1cccc(CNC2C3C4C5C3C3(OCCO3)C3C5CC4C23)c1 |TLB:13:18:11.10:20,8:22:11.10:20,THB:12:11:18.22:20,9:10:18.22:20| Show InChI InChI=1S/C20H22BrNO2/c21-10-3-1-2-9(6-10)8-22-19-15-11-7-12-14-13(11)16(19)18(14)20(17(12)15)23-4-5-24-20/h1-3,6,11-19,22H,4-5,7-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University (NEOMED) Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma-1 receptor in guinea pig brain				Bioorg Med Chem Lett 23: 1707-11 (2013) Article DOI: 10.1016/j.bmcl.2013.01.069 BindingDB Entry DOI: 10.7270/Q2G73G3N
					More data for this Ligand-Target Pair