BDBM50289088 4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-2-methyl-butyric acid::CHEMBL349248

SMILES: COc1ccc2n(Cc3ccc(Br)cc3)c(C)c(CCC(C)C(O)=O)c2c1

InChI Key: InChIKey=SHQVLLYZMUMEPR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (RAT)	BDBM50289088 (4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...) Show SMILES COc1ccc2n(Cc3ccc(Br)cc3)c(C)c(CCC(C)C(O)=O)c2c1 Show InChI InChI=1S/C22H24BrNO3/c1-14(22(25)26)4-10-19-15(2)24(13-16-5-7-17(23)8-6-16)21-11-9-18(27-3)12-20(19)21/h5-9,11-12,14H,4,10,13H2,1-3H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 6: 725-730 (1996) Article DOI: 10.1016/0960-894X(96)00100-X BindingDB Entry DOI: 10.7270/Q25B02GQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (RAT)	BDBM50289088 (4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...) Show SMILES COc1ccc2n(Cc3ccc(Br)cc3)c(C)c(CCC(C)C(O)=O)c2c1 Show InChI InChI=1S/C22H24BrNO3/c1-14(22(25)26)4-10-19-15(2)24(13-16-5-7-17(23)8-6-16)21-11-9-18(27-3)12-20(19)21/h5-9,11-12,14H,4,10,13H2,1-3H3,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1 using whole cell assay				Bioorg Med Chem Lett 6: 725-730 (1996) Article DOI: 10.1016/0960-894X(96)00100-X BindingDB Entry DOI: 10.7270/Q25B02GQ
					More data for this Ligand-Target Pair