Found 4 hits for monomerid = 50290159 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50290159
(3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethy...)Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NS(=O)(=O)C(CC(C)C)CC(O)=O Show InChI InChI=1S/C18H28N2O6S/c1-12(2)9-15(11-17(21)22)27(24,25)20-16(18(23)19-3)10-13-5-7-14(26-4)8-6-13/h5-8,12,15-16,20H,9-11H2,1-4H3,(H,19,23)(H,21,22)/t15?,16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloproteinase-2 (MMP-2) |
Bioorg Med Chem Lett 7: 2331-2336 (1997)
Article DOI: 10.1016/S0960-894X(97)00182-0
BindingDB Entry DOI: 10.7270/Q2TH8MQ4 |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50290159
(3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethy...)Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NS(=O)(=O)C(CC(C)C)CC(O)=O Show InChI InChI=1S/C18H28N2O6S/c1-12(2)9-15(11-17(21)22)27(24,25)20-16(18(23)19-3)10-13-5-7-14(26-4)8-6-13/h5-8,12,15-16,20H,9-11H2,1-4H3,(H,19,23)(H,21,22)/t15?,16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloproteinase-3 (MMP-3) |
Bioorg Med Chem Lett 7: 2331-2336 (1997)
Article DOI: 10.1016/S0960-894X(97)00182-0
BindingDB Entry DOI: 10.7270/Q2TH8MQ4 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50290159
(3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethy...)Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NS(=O)(=O)C(CC(C)C)CC(O)=O Show InChI InChI=1S/C18H28N2O6S/c1-12(2)9-15(11-17(21)22)27(24,25)20-16(18(23)19-3)10-13-5-7-14(26-4)8-6-13/h5-8,12,15-16,20H,9-11H2,1-4H3,(H,19,23)(H,21,22)/t15?,16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloproteinase-9 |
Bioorg Med Chem Lett 7: 2331-2336 (1997)
Article DOI: 10.1016/S0960-894X(97)00182-0
BindingDB Entry DOI: 10.7270/Q2TH8MQ4 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50290159
(3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethy...)Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NS(=O)(=O)C(CC(C)C)CC(O)=O Show InChI InChI=1S/C18H28N2O6S/c1-12(2)9-15(11-17(21)22)27(24,25)20-16(18(23)19-3)10-13-5-7-14(26-4)8-6-13/h5-8,12,15-16,20H,9-11H2,1-4H3,(H,19,23)(H,21,22)/t15?,16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloproteinase-1 (MMP-1) |
Bioorg Med Chem Lett 7: 2331-2336 (1997)
Article DOI: 10.1016/S0960-894X(97)00182-0
BindingDB Entry DOI: 10.7270/Q2TH8MQ4 |
More data for this
Ligand-Target Pair | |
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