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BDBM50290370 Benzyl-[1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazol-3-ylmethyl]-amine::CHEMBL314419

SMILES: Fc1ccc(cc1)-n1nc(CNCc2ccccc2)c2CCCC(Cc3cccc4ccccc34)c12

InChI Key: InChIKey=MFAKRRVZEGWVLN-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290370   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290370
PNG
(Benzyl-[1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethy...)
Show SMILES Fc1ccc(cc1)-n1nc(CNCc2ccccc2)c2CCCC(Cc3cccc4ccccc34)c12
Show InChI InChI=1S/C32H30FN3/c33-27-16-18-28(19-17-27)36-32-26(20-25-12-6-11-24-10-4-5-14-29(24)25)13-7-15-30(32)31(35-36)22-34-21-23-8-2-1-3-9-23/h1-6,8-12,14,16-19,26,34H,7,13,15,20-22H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 1.38E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair